By Liv Osby HEALTH WRITER losby@greenvillenews.com
The Greenwood Genetic Center is among 50 sites in the United
States and other countries to share $71 million in funding to
investigate rare diseases as part of a National Institutes of Health
research network.
The Rare Diseases Clinical Research Network will conduct more
than 20 studies over the next five years.
"By studying the genetic component of these rare diseases, we
hope to be able to better predict the course of the illnesses and
provide more effective, personalized treatments for those
afflicted," NIH Director Dr. Elias A. Zerhouni said in a statement.
"Ultimately, this individualized approach, completely different from
how we treat patients today, will allow us to prevent or to promptly
treat the complications arising from these genetic disorders."
Because there are so few patients affected by each disease, few
drug companies research treatments for them.
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NIH defines a rare disease as a condition that affects fewer than
200,000 people nationwide. Researchers are aware of some 6,000 such
diseases, which afflict about 25 million Americans.
Just last year, the Greenwood Genetic Center and Clemson
University announced a plan to invest $15 million to build a
graduate education center in Greenwood to train scientists to study
causes and treatments for birth disorders as well as the genetic
susceptibility to conditions such as premature birth, hypertension
and diabetes.
With the new network, the Greenwood Genetic Center will be
studying Angelman, Rett and Prader-Willi syndromes, a collection of
neurological and congenital disorders marked by mental retardation
and other symptoms, officials said.
Other diseases that will be studied include myelodysplastic
syndrome and other bone marrow failure conditions;
lymphangioleiomyomatosis (LAM), rare genetic disorders of the
airways, and other rare lung diseases; episodic ataxia,
Andersen-Tawil syndrome and nondystrophic myotonias; urea cycle
disorders; rare pediatric liver diseases; and rare genetic steroid
defects. |